iti duHkham etad iyam asya
shantir iyam ayam upaaya iti
pravibhaagashaH param idaM catuSHTayam
"This is suffering; and this, belonging to it,
Is the tangled mass of tendrils producing it;
This is inhibition; and this is a means."
He thus spelled out, one by one,
the ascendant set of four.
Here it is, straight from the horse's mouth. The word "lataa" in the second line, I think, is not a metaphor for anything. Ashvaghosha is describing the twining tendrils of individual neurones in the brain and nervous system.
iti: thus (open quotes)
duHKham: (masculine) suffering, unease, dissatisfaction
etad: (masculine) this is, here is [suffering]
iyam: (feminine, agreeing with lataa) this is, here is [the tangle]
asya: (genitive, masculine, agreeing with duHKha) of it, belonging to suffering
samudaya: combination, aggregate, mass; (with Buddhists) producing cause, instigating cause (of suffering)
lataa: (feminine) creeper, twining tendril
pravartikaa: setting in motion, causing to roll onward, causing, producing,
shanti: (feminine) peace, extinction, suppression, inhibition
iyam: (feminine) this
ayam: (masculine) this
upaaya: means, method, approach, the means-whereby
iti: thus (close quotes)
pravibhaagashaH: separately, singly, one by one
param: highest, ascendant, supreme
idam: (accusative neuter singular) this, thus, here
catuSHTayam: set of four, tetrad, foursome
And explaining in detail with its three divisions and twelve separate statements the supreme fourfold truth, which is unequalled, pre-eminent and incontrovertible, namely, 'This is suffering, this is its origin which consists in the persistence of active being, this is its suppression and this the means,' He converted first of all him of the Kaundinya gotra.
"This is suffering, this is the network of causes producing it, this is its pacification, this is the means." Thus the seer separately set forth the highest fourfold truth which is unequaled, incontrovertible and supreme, with its three divisions and twelve connecting statements, and he guided to insight firstly a man from the Kaundina clan.